Pertussis toxin-induced inhibition of Wnt/β-catenin signaling in dendritic cells promotes an autoimmune response in experimental autoimmune uveitis.

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作者： Zhihui,Zhang ^[1] ; Yongtao,Li ^[1] ; Nu,Chen ^[1] ; Huan,Li ^[1] ; Shuang,Chen ^[1] ; Xuexue,Cui ^[1] ; Hui,Shao ^[2] ; Lai,Wei ^[3] ; Jianxing,Ma ^[4] ; Song,Zhang ^[5] ; Xiaorong,Li ^[1] ; Xiaomin,Zhang ^[6]

作者单位： Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China. ^[1] Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, School of Medicine, Louisville, KY, USA. ^[2] State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. ^[3] Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA. ^[4] Institute for Immunology and College of Life Sciences, Nankai University, Tianjin, China. ^[5] Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China. xzhang08@tmu.edu.cn. ^[6]

关键词 Dendritic cells Experimental autoimmune uveitis Pathogenic T cell Pertussis toxin