Verbenalin attenuates hepatic damage and mitochondrial dysfunction in alcohol-associated steatohepatitis by regulating MDMX/PPARα-mediated ferroptosis.

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第一作者： Jiahui,Dong

第一单位： Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China.

作者： Jiahui,Dong ^[1] ; Changlin,Du ^[1] ; Chuanting,Xu ^[1] ; Qi,Wang ^[1] ; Zhonghao,Wang ^[1] ; Qian,Zhu ^[1] ; Xiongwen,Lv ^[2] ; Lei,Zhang ^[2] ; Jun,Li ^[1] ; Cheng,Huang ^[1] ; Hua,Wang ^[3] ; Taotao,Ma ^[4]

作者单位： Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China. ^[1] Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Center of Traditional Chinese Medicine Formula Granule, Anhui Medical University, China. ^[2] Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230036, China. Electronic address: wanghua@ahmu.edu.cn. ^[3] Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Center of Traditional Chinese Medicine Formula Granule, Anhui Medical University, China. Electronic address: mataotao@ahmu.edu.cn. ^[4]

关键词 Alcoholic steatohepatitis Ferroptosis MDMX PPARα Verbenalin