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miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy.

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第一作者： Mary,Xylaki

第一单位： Department of Experimental Neurodegeneration, Centre for Biostructural Imaging of Neurodegeneration, University Medical Centre Göttingen, Göttingen, Germany.

作者： Mary,Xylaki ^[1] ; Isabel,Paiva ^[2] ; Mohammed,Al-Azzani ^[1] ; Ellen,Gerhardt ^[1] ; Gaurav,Jain ^[3] ; Md Rezaul,Islam ^[3] ; Eftychia,Vasili ^[1] ; Zinah,Wassouf ^[1] ; Julia M,Schulze-Hentrich ^[4] ; André,Fischer ^[5] ; Tiago Fleming,Outeiro ^[6]

作者单位： Department of Experimental Neurodegeneration, Centre for Biostructural Imaging of Neurodegeneration, University Medical Centre Göttingen, Göttingen, Germany. ^[1] Department of Experimental Neurodegeneration, Centre for Biostructural Imaging of Neurodegeneration, University Medical Centre Göttingen, Göttingen, Germany.;Present address: Laboratory of Cognitive and Adaptive Neuroscience, UMR 7364 (CNRS/ Strasbourg University), Strasbourg, France. ^[2] Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Centre for Neurodegenerative Diseases (DZNE), Göttingen, Germany. ^[3] Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany. ^[4] Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Centre for Neurodegenerative Diseases (DZNE), Göttingen, Germany.;Department of Psychiatry and Psychotherapy, University Medical Centre, Göttingen, Germany.;Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany. ^[5] Department of Experimental Neurodegeneration, Centre for Biostructural Imaging of Neurodegeneration, University Medical Centre Göttingen, Göttingen, Germany.;Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.;Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle Upon Tyne, UK.;Scientific employee with an honorary contract at German Centre for Neurodegenerative Diseases (DZNE), Göttingen, Germany. ^[6]

关键词 Alpha-synuclein dendritic spines miRNA neuronal plasticity synucleinopathy