A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains.

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作者： Vanessa R,Montoya ^[1] ; Trine M,Ready ^[2] ; Abby,Felton ^[2] ; Sydney R,Fine ^[2] ; Molly,OhAinle ^[2] ; Michael,Emerman ^[2]

作者单位： Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, USA. ^[1] Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Center, Seattle, Washington, USA. ^[2]

关键词 CRISPR screen T cells dependency factor human immunodeficiency virus transcription factors virus replication

主题词人类(Humans);HIV-1(HIV-1);病毒复制(Virus Replication);细胞系(Cell Line);HIV感染(HIV Infections);宿主与病原体相互作用(Host-Pathogen Interactions);转录因子(Transcription Factors);辅阻遏蛋白质类(Co-Repressor Proteins);阳离子转运蛋白质类(Cation Transport Proteins);泛素缀合酶类(Ubiquitin-Conjugating Enzymes)

DOI 10.1128/mbio.00009-23

PMID 36744886

发布时间 2023-03-14

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A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains.

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