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首页> Veterinary and comparative oncology> Establishment of a BRAF V595E-mutant canine prostate cancer cell line and the antitumor effects of MEK inhibitors against canine prostate cancer.

Establishment of a BRAF V595E-mutant canine prostate cancer cell line and the antitumor effects of MEK inhibitors against canine prostate cancer.

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作者： Masanori,Kobayashi ^[1] ; Moe,Onozawa ^[1] ; Shiho,Watanabe ^[1] ; Tomokazu,Nagashima ^[2] ; Kyoichi,Tamura ^[3] ; Yoshiaki,Kubo ^[4] ; Akiko,Ikeda ^[1] ; Kazuhiko,Ochiai ^[5] ; Masaki,Michishita ^[2] ; Makoto,Bonkobara ^[3] ; Masato,Kobayashi ^[1] ; Tatsuya,Hori ^[1] ; Eiichi,Kawakami ^[1]

作者单位： Laboratory of Reproduction, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan. ^[1] Laboratory of Veterinary Pathology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan. ^[2] Laboratory of Veterinary Clinical Pathology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan. ^[3] Veterinary Medical Teaching Hospital, Nippon Veterinary and Life Science University, Tokyo, Japan. ^[4] Laboratory of Veterinary Hygiene, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan. ^[5] Japan Institute of Small Animal Reproduction (Bio Art), Tokyo, Japan. ^[6]

关键词 BRAF MEK inhibitor canine phosphorylation prostate cancer

主题词男(雄)性(Male);人类(Humans);动物(Animals);狗(Dogs);小鼠(Mice);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);细胞系, 肿瘤(Cell Line, Tumor);狗疾病(Dog Diseases);蛋白激酶抑制剂(Protein Kinase Inhibitors);丝裂原激活蛋白激酶激酶类(Mitogen-Activated Protein Kinase Kinases);前列腺肿瘤(Prostatic Neoplasms);突变(Mutation)

DOI 10.1111/vco.12879

PMID 36745053

发布时间 2024-01-02

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Veterinary and comparative oncology

Veterinary and comparative oncology

2023年21卷2期

221-230页

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