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首页> Xenobiotica; the fate of foreign compounds in biological systems> Mass balance study of [<sup>14</sup>C]SHR0302, a selective and potent JAK1 inhibitor in humans.

Mass balance study of [<sup>14</sup>C]SHR0302, a selective and potent JAK1 inhibitor in humans.

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作者： Xinyu,Ge ^[1] ; Sheng,Ma ^[2] ; Shu,Yan ^[3] ; Yali,Wu ^[4] ; Chong,Chen ^[2] ; Chongzhuang,Tang ^[2] ; Yan,Zhan ^[1] ; Yi-Cong,Bian ^[2] ; Kai,Shen ^[2] ; Sheng,Feng ^[2] ; Xuehu,Gao ^[3] ; Dafang,Zhong ^[4] ; Hua,Zhang ^[5] ; Li-Yan,Miao ^[5] ; Xing-Xing,Diao ^[5]

作者单位： School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ^[1] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. ^[2] Department of Pharmacy, the First Affiliated Hospital of Soochow University, Suzhou, China. ^[3] Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China. ^[4] Jiangsu Hengrui Medicine Co., Ltd, Lianyungang, China. ^[5] College of Pharmaceutical Sciences, Soochow University, Suzhou, China. ^[6] National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Jiangsu, China. ^[7]

关键词 JAK1 inhibitor SHR0302 [14C]SHR0302 mass balance radioactivity

主题词人类(Humans);男(雄)性(Male);硫酸类(Sulfuric Acids);粪便(Feces);体液(Body Fluids);投药, 口服(Administration, Oral);碳放射性同位素(Carbon Radioisotopes);Janus激酶1(Janus Kinase 1)

DOI 10.1080/00498254.2023.2176267

PMID 36745485

发布时间 2023-05-10

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Xenobiotica; the fate of foreign compounds in biological systems

Xenobiotica; the fate of foreign compounds in biological systems

2023年53卷2期

69-83页

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Xenobiotica; the fate of foreign compounds in biological systems

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Xenobiotica; the fate of foreign compounds in biological systems

2023年53卷2期

69-83页

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