Oncofetal protein glypican-3 is a biomarker and critical regulator of function for neuroendocrine cells in prostate cancer.

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作者： William,Butler ^[1] ; Lingfan,Xu ^[1] ; Yinglu,Zhou ^[2] ; Qing,Cheng ^[3] ; J Spencer,Hauck ^[1] ; Yiping,He ^[1] ; Robert,Marek ^[4] ; Zachary,Hartman ^[1] ; Liang,Cheng ^[3] ; Qing,Yang ^[4] ; Mu-En,Wang ^[5] ; Ming,Chen ^[6] ; Hong,Zhang ^[7] ; Andrew J,Armstrong ^[1] ; Jiaoti,Huang ^[1]

作者单位： Department of Pathology, Duke University School of Medicine, Durham, NC, USA. ^[1] Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA. ^[2] Department of Surgery, Duke University School of Medicine, Durham, NC, USA. ^[3] Duke Cancer Institute, Duke University, Durham, NC, USA. ^[4] Department of Immunology, Duke University School of Medicine, Durham, NC, USA. ^[5] Department of Pathology and Laboratory Medicine, Lifespan Academic Medical Center, Legorreta Cancer Center, Brown University Warren Alpert Medical School, Providence, RI, USA. ^[6] School of Nursing, Duke University School of Medicine, Durham, NC, USA. ^[7] Duke Cancer Institute Center for Prostate and Urologic Cancers, Divisions of Medical Oncology and Urology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA. ^[8] Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA. ^[9]

关键词 biomarkers cellular heterogeneity genitourinary oncology immunotherapy neuroendocrine precision oncology prostate cancer

主题词男(雄)性(Male);人类(Humans);神经内分泌细胞(Neuroendocrine Cells);磷脂酰肌醇蛋白聚糖类(Glypicans);腺癌(Adenocarcinoma);肿瘤复发, 局部(Neoplasm Recurrence, Local);前列腺肿瘤(Prostatic Neoplasms)

DOI 10.1002/path.6063

PMID 36752189

发布时间 2024-05-02

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