IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.

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第一作者： Hua,Chao

第一单位： Division of Plastic and Reconstructive Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

作者： Hua,Chao ^[1] ; Lisheng,Zheng ^[2] ; Pojui,Hsu ^[1] ; Jinyun,He ^[1] ; Ridong,Wu ^[3] ; Shuqia,Xu ^[1] ; Ruixi,Zeng ^[1] ; Yuan,Zhou ^[1] ; Huisi,Ma ^[4] ; Haibo,Liu ^[1] ; Qing,Tang ^[1]

作者单位： Division of Plastic and Reconstructive Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[1] Department of Pathology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China. ^[2] Division of Vascular Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[3] Department of Pathology, Foshan Women and Children's Hospital, Foshan, China. ^[4]

关键词 Dermatology Fibrosis Inflammation Skin

主题词动物(Animals);人类(Humans);小鼠(Mice);减量调节(Down-Regulation);细胞外基质(Extracellular Matrix);成纤维细胞(Fibroblasts);瘢痕疙瘩(Keloid);坏死(Necrosis);STAT6转录因子(STAT6 Transcription Factor);Janus激酶类(Janus Kinases)

DOI 10.1172/jci.insight.157091

PMID 36757802

发布时间 2023-04-06

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IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.

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IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.

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