Replacement substance P reduces cardiac fibrosis in monkeys with type 2 diabetes.

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作者： Giselle C,Meléndez ^[1] ; Kylie,Kavanagh ^[2] ; Nazli,Gharraee ^[3] ; Jessica L,Lacy ^[3] ; Kevin H,Goslen ^[4] ; Masha,Block ^[5] ; Jordyn,Whitfield ^[5] ; Alexander,Widiapradja ^[6] ; Scott P,Levick ^[6]

作者单位： Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA. Electronic address: gmelende@wakehealth.edu. ^[1] Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; College of Health and Medicine, The University of Tasmania, Hobart, TAS, Australia. ^[2] Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA. ^[3] Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA. ^[4] Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA. ^[5] Kolling Institute, Royal North Shore Hospital, St Leonards, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia; Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV, USA. ^[6]

关键词 Cardiomyopathy Fibrosis Heart Non-human primate

主题词女(雌)性(Female);小鼠(Mice);动物(Animals);糖尿病, 2型(Diabetes Mellitus, Type 2);P物质(Substance P);每搏输出量(Stroke Volume);心室功能, 左(Ventricular Function, Left);糖尿病, 实验性(Diabetes Mellitus, Experimental);心肌疾病(Cardiomyopathies);纤维化(Fibrosis);心肌(Myocardium)

DOI 10.1016/j.biopha.2023.114365

PMID 36758315

发布时间 2024-07-17

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2023年160卷

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Replacement substance P reduces cardiac fibrosis in monkeys with type 2 diabetes.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Replacement substance P reduces cardiac fibrosis in monkeys with type 2 diabetes.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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