换一批
换一批IL-17A-producing CD8<sup>+</sup> T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts.
作者：
Felix Simon Ruben,Picard [1]
;
Veronika,Lutz [1]
;
Anna,Brichkina [2]
;
Felix,Neuhaus [1]
;
Teresa,Ruckenbrod [1]
;
Anna,Hupfer [2]
;
Hartmann,Raifer [3]
;
Matthias,Klein [4]
;
Tobias,Bopp [4]
;
Petra Ina,Pfefferle [5]
;
Rajkumar,Savai [6]
;
Immo,Prinz [7]
;
Ari,Waisman [8]
;
Sonja,Moos [8]
;
Hyun-Dong,Chang [9]
;
Stefan,Heinrich [10]
;
Detlef K,Bartsch [11]
;
Malte,Buchholz [2]
;
Shiv,Singh [12]
;
Mengyu,Tu [12]
;
Lukas,Klein [12]
;
Christian,Bauer [2]
;
Robert,Liefke [13]
;
Andreas,Burchert [14]
;
Ho-Ryun,Chung [15]
;
Philipp,Mayer [16]
;
Thomas M,Gress [2]
;
Matthias,Lauth [2]
;
Matthias,Gaida [17]
;
Magdalena,Huber [18]
作者单位：
Institute of Systems Immunology, Philipps-University Marburg, Marburg, Germany.
[1]
Department of Gastroenterology, Endocrinology, Metabolism and Infection, Center for Tumor and Immunology (ZTI), Philipps-University Marburg, Marburg, Germany.
[2]
Institute of Systems Immunology, Philipps-University Marburg, Marburg, Germany.;Core-Facility Flow Cytometry, Philipps-University Marburg, Marburg, Germany.
[3]
Institute for Immunology, University Medical Center, Johannes Gutenberg University, Mainz, Germany.
[4]
Comprehensive Biomaterial Bank Marburg (CBBMR), Philipps-Universitat Marburg, Marburg, Germany.
[5]
Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Justus Liebig Universitat, Giessen, Germany.;Department of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
[6]
Institute of Systems Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[7]
Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
[8]
Institute of Biotechnology, Technische Universität, Berlin, Germany.;German Rheumatism Research Center (DRFZ), An Institute of the Leibniz Association, Berlin, Germany.
[9]
Department of Surgery, Johannes Gutenberg University, Mainz, Germany.
[10]
Division of Visceral, Thoracic and Vascular Surgery, Philipps-University Marburg, Marburg, Germany.
[11]
Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, Goettingen, Germany.
[12]
Institute of Molecular Biology and Tumor Research (IMT), Philipps-University Marburg, Marburg, Germany.
[13]
Department of Hematology, Oncology and Immunology, Philipps University Marburg Faculty of Medicine, Marburg, Germany.
[14]
Institute for Medical Bioinformatics and Biostatistics, Philipps-University Marburg, Marburg, Germany.
[15]
Department of Diagnostic and Interventional Radiology, Heidelberg University, Heidelberg, Germany.
[16]
Institute of Pathology, JGU Mainz, Mainz, Germany.;Research Center for Immunotherapy, University Medical Center Mainz, JGU-Mainz, Mainz, Germany.;Joint Unit Immunopathology, Institute of Pathology, University Medical Center, JGU-Mainz and TRON, Translational Oncology at the University Medical Center, JGU-Mainz, Mainz, Germany.
[17]
Institute of Systems Immunology, Philipps-University Marburg, Marburg, Germany magdalena.huber@staff.uni-marburg.de.
[18]
主题词
人类(Humans);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);白细胞介素17(Interleukin-17);胰腺肿瘤(Pancreatic Neoplasms);癌, 胰腺管(Carcinoma, Pancreatic Ductal);同源盒结构域蛋白质类(Homeodomain Proteins)
DOI
10.1136/gutjnl-2022-327855
PMID
36759154
发布时间
2024-08-06
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