Specific myeloid signatures in peripheral blood differentiate active and rare clinical phenotypes of multiple sclerosis.

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第一作者： Aigli G,Vakrakou

第一单位： Demyelinating Diseases Unit, 1st Department of Neurology, School of Medicine, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.;Department of Neuropathology, University of Göttingen Medical Center, Göttingen, Germany.

作者： Aigli G,Vakrakou ^[1] ; Nikolaos,Paschalidis ^[2] ; Eleftherios,Pavlos ^[3] ; Christina,Giannouli ^[4] ; Dimitris,Karathanasis ^[5] ; Xristina,Tsipota ^[5] ; Georgios,Velonakis ^[6] ; Christine,Stadelmann-Nessler ^[7] ; Maria-Eleftheria,Evangelopoulos ^[5] ; Leonidas,Stefanis ^[5] ; Constantinos,Kilidireas ^[8]

作者单位： Demyelinating Diseases Unit, 1st Department of Neurology, School of Medicine, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.;Department of Neuropathology, University of Göttingen Medical Center, Göttingen, Germany. ^[1] Mass Cytometry-CyTOF Laboratory, Center for Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. ^[2] Center for Clinical Research, Experimental Surgery and Translational Research Biomedical Research Foundation of the Academy of Athens, Athens, Greece.;Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece. ^[3] Center for Clinical Research, Experimental Surgery and Translational Research Biomedical Research Foundation of the Academy of Athens, Athens, Greece. ^[4] Demyelinating Diseases Unit, 1st Department of Neurology, School of Medicine, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece. ^[5] Research Unit of Radiology, 2nd Department of Radiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece. ^[6] Department of Neuropathology, University of Göttingen Medical Center, Göttingen, Germany. ^[7] Demyelinating Diseases Unit, 1st Department of Neurology, School of Medicine, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.;Department of Neurology, Henry Dunant Hospital Center, Athens, Greece. ^[8]

关键词 B cells NK cells T cells macrophages mass cytometry multiple sclerosis myeloid-signature tumefactive multiple sclerosis

主题词人类(Humans);多发性硬化(Multiple Sclerosis);表型(Phenotype)

DOI 10.3389/fimmu.2023.1071623

PMID 36761741

发布时间 2023-03-07

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