Associations Between Plasma Klotho with Renal Function and Cerebrospinal Fluid Amyloid-β Levels in Alzheimer's Disease: The Chongqing Ageing & Dementia Study.

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第一作者： Jun-Rong,Ren

第一单位： Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China.;Institute of Brain and Intelligence, Third Military Medical University, Chongqing, China.;Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, China.

作者： Jun-Rong,Ren ^[1] ; Zhen,Wang ^[2] ; Yuan,Cheng ^[1] ; Chen-Yang,He ^[1] ; Jie-Ming,Jian ^[1] ; Dong-Yu,Fan ^[1] ; Ying-Ying,Shen ^[1] ; Dong-Wan,Chen ^[1] ; Hui-Yun,Li ^[1] ; Xu,Yi ^[1] ; Gui-Hua,Zeng ^[1] ; Cheng-Rong,Tan ^[1] ; An-Yu,Shi ^[1] ; Li-Yong,Chen ^[3] ; Qing-Xiang,Mao ^[3] ; Yan-Jiang,Wang ^[4] ; Jun,Wang ^[1]

作者单位： Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China.;Institute of Brain and Intelligence, Third Military Medical University, Chongqing, China.;Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, China. ^[1] Department of Critical Care Medicine, Daping Hospital, Third Military Medical University, Chongqing, China. ^[2] Department of Anaesthesiology, Daping Hospital, Third Military Medical University, Chongqing, China. ^[3] Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China.;Institute of Brain and Intelligence, Third Military Medical University, Chongqing, China.;Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, China.;Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, China.;Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.;State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China. ^[4]

关键词 Alzheimer’s disease Klotho amyloid-β estimated glomerular filtration rate kidney-brain crosstalk

主题词人类(Humans);衰老(Aging);阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);脑(Brain);肽碎片(Peptide Fragments);tau蛋白质类(tau Proteins)

DOI 10.3233/JAD-221107

PMID 36776069

发布时间 2023-03-31

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