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Quantifying portable genetic effects and improving cross-ancestry genetic prediction with GWAS summary statistics.

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第一作者： Jiacheng,Miao

第一单位： Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA.

作者： Jiacheng,Miao ^[1] ; Hanmin,Guo ^[2] ; Gefei,Song ^[1] ; Zijie,Zhao ^[1] ; Lin,Hou ^[3] ; Qiongshi,Lu ^[4]

作者单位： Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA. ^[1] Center for Statistical Science, Department of Industrial Engineering, Tsinghua University, Beijing, 100084, China. ^[2] Center for Statistical Science, Department of Industrial Engineering, Tsinghua University, Beijing, 100084, China. houl@tsinghua.edu.cn.;MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, 100084, China. houl@tsinghua.edu.cn. ^[3] Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA. qlu@biostat.wisc.edu.;Department of Statistics, University of Wisconsin-Madison, Madison, WI, 53706, USA. qlu@biostat.wisc.edu.;Center for Demography of Health and Aging, University of Wisconsin-Madison, Madison, WI, 53706, USA. qlu@biostat.wisc.edu. ^[4]

医学主题词人类(Humans);全基因组关联研究(Genome-Wide Association Study);多态性, 单核苷酸(Polymorphism, Single Nucleotide);危险因素(Risk Factors);多因子遗传(Multifactorial Inheritance);疾病遗传易感性(Genetic Predisposition to Disease)

DOI 10.1038/s41467-023-36544-7

PMID 36788230

发布时间 2024-09-12

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