RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression.

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作者： Abigail L,Keever ^[1] ; Kathryn M,Collins ^[2] ; Rachel A,Clark ^[2] ; Amber L,Framstad ^[2] ; Jason W,Ashley ^[2]

作者单位： Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, United States. ^[1] Department of Biology, Eastern Washington University, Cheney, WA, United States. ^[2]

关键词 ATAC-seq Macrophages Osteoclasts RANK signaling RNA-seq Sexual dimorphism

主题词小鼠(Mice);动物(Animals);女(雌)性(Female);男(雄)性(Male);破骨细胞(Osteoclasts);信号传导(Signal Transduction);小鼠, 近交C57BL(Mice, Inbred C57BL);基因表达(Gene Expression);染色质(Chromatin);后成说, 遗传(Epigenesis, Genetic)

DOI 10.7717/peerj.14814

PMID 36788807

发布时间 2023-04-28

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2023年11卷

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RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression.

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RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression.

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