Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-𝜅B-IL-6 axis of tumor-associated macrophages.

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第一作者： Boxuan,Zhou

第一单位： Department of Breast Surgery, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China.

作者： Boxuan,Zhou ^[1] ; Zhaohong,Mo ^[2] ; Guie,Lai ^[3] ; Xiaohong,Chen ^[1] ; Ruixi,Li ^[4] ; Runxin,Wu ^[5] ; Jia,Zhu ^[6] ; Fang,Zheng ^[7]

作者单位： Department of Breast Surgery, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China. ^[1] Medical Research Center and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ^[2] Department of Hepatobiliary Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, China. ^[3] Department of Laboratory, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China. ^[4] Department of Hepatobiliary and Pancreatic Surgery, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518033, China. ^[5] Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China. ^[6] Department of Breast Surgery, the First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. Zhujia888618@163.com. ^[7] Medical Research Center and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. zhengf9@mail.sysu.edu.cn. ^[8]

关键词 Breast cancer Exosome Nanoparticles Tumor-associated macrophages cSERPINE2