首页> Clinical epigenetics> A miRNA screening identifies miR-192-5p as associated with response to azacitidine and lenalidomide therapy in myelodysplastic syndromes.

A miRNA screening identifies miR-192-5p as associated with response to azacitidine and lenalidomide therapy in myelodysplastic syndromes.

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第一作者： Sara,Mongiorgi

第一单位： Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126, Bologna, Italy.

作者： Sara,Mongiorgi ^[1] ; Alessia,De Stefano ^[1] ; Stefano,Ratti ^[1] ; Valentina,Indio ^[2] ; Annalisa,Astolfi ^[3] ; Irene,Casalin ^[1] ; Andrea,Pellagatti ^[4] ; Stefania,Paolini ^[5] ; Sarah,Parisi ^[5] ; Michele,Cavo ^[5] ; Andrea,Pession ^[6] ; James A,McCubrey ^[7] ; Pann-Ghill,Suh ^[8] ; Lucia,Manzoli ^[1] ; Jacqueline,Boultwood ^[4] ; Carlo,Finelli ^[5] ; Lucio,Cocco ^[9] ; Matilde Y,Follo ^[10]

作者单位： Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126, Bologna, Italy. ^[1] "Giorgio Prodi" Cancer Research Center, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy. ^[2] Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy. ^[3] Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, and Oxford BRC Haematology Theme, Oxford, OX3 9DU, UK. ^[4] IRCCS - Azienda Ospedaliero-Universitaria di Bologna, Institute of Hematology " L. e A. Seràgnoli", University of Bologna, Via Massarenti 9, 40138, Bologna, Italy. ^[5] IRCCS Azienda Ospedaliero-Universitaria di Bologna, Division of Pediatrics, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy. ^[6] Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, 27858, USA. ^[7] Korea Brain Research Institute, Daegu, 41062, South Korea. ^[8] Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126, Bologna, Italy. lucio.cocco@unibo.it. ^[9] Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126, Bologna, Italy. matilde.follo@unibo.it. ^[10]

关键词 Azacitidine BCL2 Lenalidomide Myelodysplastic syndromes miRNA profiling

医学主题词人类(Humans);阿扎胞苷(Azacitidine);微RNAs(MicroRNAs);DNA甲基化(DNA Methylation);骨髓增生异常综合征(Myelodysplastic Syndromes);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2)

DOI 10.1186/s13148-023-01441-9

PMID 36803590

发布时间 2023-03-20

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