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Determination of the intermediates in glycolysis and tricarboxylic acid cycle with an improved derivatization strategy using gas chromatography-mass spectrometry in complex samples.

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第一作者： Wei,Li

第一单位： National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China.

作者： Wei,Li ^[1] ; Jiangyan,Huo ^[2] ; Entezar,Berik ^[3] ; Wenyong,Wu ^[4] ; Jinjun,Hou ^[2] ; Huali,Long ^[2] ; Min,Lei ^[1] ; Zhaoxia,Li ^[5] ; Zijia,Zhang ^[6] ; Wanying,Wu ^[7]

作者单位： National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China. ^[1] National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. ^[2] National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Beijing Key Lab of TCM Collateral Disease Theory Research, School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China. ^[3] National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210029, China. ^[4] Beijing Key Lab of TCM Collateral Disease Theory Research, School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China. Electronic address: gmacli@ccmu.edu.cn. ^[5] National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: zijiazhang@simm.ac.cn. ^[6] National Engineering Research Center of TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: wanyingwu@simm.ac.cn. ^[7]

关键词 Complex sample Derivatization GC–MS Glycolysis Shenqi Fuzheng Injection TCA cycle Traditional Chinese medicine

医学主题词人类(Humans);柠檬酸循环(Citric Acid Cycle);气相色谱-质谱法(Gas Chromatography-Mass Spectrometry);糖酵解(Glycolysis);柠檬酸(Citric Acid);萎缩(Atrophy)

DOI 10.1016/j.chroma.2023.463856

PMID 36803770

发布时间 2023-02-28

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