首页> The American journal of pathology> Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network.

Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network.

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第一作者： Stefan C,Halvorsen

第一单位： Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts.

作者： Stefan C,Halvorsen ^[1] ; Yair,Benita ^[1] ; Megan,Hopton ^[1] ; Brooke,Hoppe ^[1] ; Hilmar O,Gunnlaugsson ^[1] ; Parimal,Korgaonkar ^[1] ; Charles R,Vanderburg ^[2] ; G Petur,Nielsen ^[3] ; Nicole,Trepanowski ^[1] ; Jaime H,Cheah ^[4] ; Matthew P,Frosch ^[5] ; Joseph H,Schwab ^[6] ; Andrew E,Rosenberg ^[3] ; Francis J,Hornicek ^[7] ; Slim,Sassi ^[8]

作者单位： Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts. ^[1] Harvard NeuroDiscovery Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts. ^[2] Department of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts. ^[3] High Throughput Sciences Facility, Koch Institute of MIT, Cambridge, Massachusetts. ^[4] C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown, Massachusetts. ^[5] Department of Orthopedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts. ^[6] Department of Orthopedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: fjh21@med.miami.edu. ^[7] Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts; Department of Orthopedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: ssassi@ccib.mgh.harvard.edu. ^[8]

医学主题词人类(Humans);脊索瘤(Chordoma);脊索(Notochord);T盒域蛋白质类(T-Box Domain Proteins);转化生长因子β(Transforming Growth Factor beta);转化生长因子β1(Transforming Growth Factor beta1)

DOI 10.1016/j.ajpath.2023.01.014

PMID 36804377

发布时间 2025-01-03

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