Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis.

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第一作者： Ângelo Ferreira,Chora

第一单位： Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal. Electronic address: angelochora@medicina.ulisboa.pt.

作者： Ângelo Ferreira,Chora ^[1] ; Sofia,Marques ^[2] ; Joana Lisboa,Gonçalves ^[2] ; Priscila,Lima ^[2] ; Daniel,Gomes da Costa ^[2] ; Daniel,Fernandez-Ruiz ^[3] ; Maria Inês,Marreiros ^[2] ; Pedro,Ruivo ^[2] ; Tânia,Carvalho ^[2] ; Ruy M,Ribeiro ^[4] ; Karine,Serre ^[2] ; William R,Heath ^[5] ; Bruno,Silva-Santos ^[2] ; Ann T,Tate ^[6] ; Maria M,Mota ^[7]

作者单位： Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal. Electronic address: angelochora@medicina.ulisboa.pt. ^[1] Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal. ^[2] Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia. ^[3] Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. ^[4] Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia; ARC Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Parkville, VIC 3010, Australia. ^[5] Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA. ^[6] Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal. Electronic address: mmota@medicina.ulisboa.pt. ^[7]

关键词 IL-17 Plasmodium infection acquired immunity cerebral malaria gamma-delta T cells malaria reticulocytes splenic erythropoiesis