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A proteomic survival predictor for COVID-19 patients in intensive care.

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作者: Vadim,Demichev [1] ; Pinkus,Tober-Lau [2] ; Tatiana,Nazarenko [3] ; Oliver,Lemke [4] ; Simran,Kaur Aulakh [5] ; Harry J,Whitwell [6] ; Annika,Röhl [4] ; Anja,Freiwald [4] ; Mirja,Mittermaier [7] ; Lukasz,Szyrwiel [5] ; Daniela,Ludwig [4] ; Clara,Correia-Melo [5] ; Lena J,Lippert [2] ; Elisa T,Helbig [2] ; Paula,Stubbemann [2] ; Nadine,Olk [2] ; Charlotte,Thibeault [2] ; Nana-Maria,Grüning [4] ; Oleg,Blyuss [8] ; Spyros,Vernardis [5] ; Matthew,White [5] ; Christoph B,Messner [9] ; Michael,Joannidis [10] ; Thomas,Sonnweber [11] ; Sebastian J,Klein [10] ; Alex,Pizzini [11] ; Yvonne,Wohlfarter [12] ; Sabina,Sahanic [11] ; Richard,Hilbe [11] ; Benedikt,Schaefer [13] ; Sonja,Wagner [13] ; Felix,Machleidt [2] ; Carmen,Garcia [2] ; Christoph,Ruwwe-Glösenkamp [2] ; Tilman,Lingscheid [2] ; Laure,Bosquillon de Jarcy [2] ; Miriam S,Stegemann [2] ; Moritz,Pfeiffer [2] ; Linda,Jürgens [2] ; Sophy,Denker [14] ; Daniel,Zickler [15] ; Claudia,Spies [16] ; Andreas,Edel [16] ; Nils B,Müller [15] ; Philipp,Enghard [15] ; Aleksej,Zelezniak [17] ; Rosa,Bellmann-Weiler [11] ; Günter,Weiss [11] ; Archie,Campbell [18] ; Caroline,Hayward [19] ; David J,Porteous [18] ; Riccardo E,Marioni [20] ; Alexander,Uhrig [2] ; Heinz,Zoller [13] ; Judith,Löffler-Ragg [11] ; Markus A,Keller [12] ; Ivan,Tancevski [11] ; John F,Timms [21] ; Alexey,Zaikin [22] ; Stefan,Hippenstiel [23] ; Michael,Ramharter [24] ; Holger,Müller-Redetzky [2] ; Martin,Witzenrath [23] ; Norbert,Suttorp [23] ; Kathryn,Lilley [25] ; Michael,Mülleder [26] ; Leif Erik,Sander [23] ; PA-COVID-19 Study group [27] ; Florian,Kurth [9] ; Markus,Ralser
作者单位: Charité-Universitätsmedizin Berlin, Department of Biochemistry, Berlin, Germany.;The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, United Kingdom.;The University of Cambridge, Department of Biochemistry and Cambridge Centre for Proteomics, Cambridge, United Kingdom. [1] Charité-Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany. [2] University College London, Department of Mathematics, London, United Kingdom.;University College London, Department of Women's Cancer, EGA Institute for Women's Health, London, United Kingdom. [3] Charité-Universitätsmedizin Berlin, Department of Biochemistry, Berlin, Germany. [4] The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, United Kingdom. [5] National Phenome Centre and Imperial Clinical Phenotyping Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.;Lobachevsky University, Laboratory of Systems Medicine of Healthy Ageing, Nizhny Novgorod, Russia.;Imperial College London, Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, London, United Kingdom. [6] Charité-Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany.;Berlin Institute of Health, Berlin, Germany. [7] Lobachevsky University, Department of Applied Mathematics, Nizhny Novgorod, Russia.;University of Hertfordshire, School of Physics, Astronomy and Mathematics, Hatfield, United Kingdom.;Sechenov First Moscow State Medical University, Department of Paediatrics and Paediatric Infectious Diseases, Moscow, Russia. [8] Charité-Universitätsmedizin Berlin, Department of Biochemistry, Berlin, Germany.;The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, United Kingdom. [9] Medical University Innsbruck, Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Innsbruck, Austria. [10] Medical University of Innsbruck, Department of Internal Medicine II, Innsbruck, Austria. [11] Medical University of Innsbruck, Institute of Human Genetics, Innsbruck, Austria. [12] Medical University of Innsbruck, Christian Doppler Laboratory for Iron and Phosphate Biology, Department of Internal Medicine I, Innsbruck, Austria. [13] Charité-Universitätsmedizin Berlin, Medical Department of Hematology, Oncology & Tumor Immunology, Virchow Campus & Molekulares Krebsforschungszentrum, Berlin, Germany. [14] Charité-Universitätsmedizin Berlin, Department of Nephrology and Internal Intensive Care Medicine, Berlin, Germany. [15] Charité-Universitätsmedizin Berlin, Department of Anesthesiology and Intensive Care, Berlin, Germany. [16] The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, United Kingdom.;Chalmers University of Technology, Department of Biology and Biological Engineering, Gothenburg, Sweden. [17] University of Edinburgh, Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, United Kingdom.;University of Edinburgh, Usher Institute, Edinburgh, United Kingdom. [18] University of Edinburgh, MRC Human Genetics Unit, Institute of Genetics and Cancer, Edinburgh, United Kingdom. [19] University of Edinburgh, Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, United Kingdom. [20] University College London, Department of Women's Cancer, EGA Institute for Women's Health, London, United Kingdom. [21] University College London, Department of Mathematics, London, United Kingdom.;University College London, Department of Women's Cancer, EGA Institute for Women's Health, London, United Kingdom.;Lobachevsky University, Laboratory of Systems Medicine of Healthy Ageing, Nizhny Novgorod, Russia.;Centre for Analysis of Complex Systems, Sechenov First Moscow State Medical University, Moscow, Russia. [22] Charité-Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany.;German Centre for Lung Research, Germany. [23] Bernhard Nocht Institute for Tropical Medicine, Department of Tropical Medicine, and University Medical Center Hamburg-Eppendorf, Department of Medicine, Hamburg, Germany. [24] The University of Cambridge, Department of Biochemistry and Cambridge Centre for Proteomics, Cambridge, United Kingdom. [25] Charité-Universitätsmedizin Berlin, Core Facility-High-Throughput Mass Spectrometry, Berlin, Germany. [26] Charité-Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany.;Bernhard Nocht Institute for Tropical Medicine, Department of Tropical Medicine, and University Medical Center Hamburg-Eppendorf, Department of Medicine, Hamburg, Germany. [27]
DOI 10.1371/journal.pdig.0000007
PMID 36812516
发布时间 2024-11-27
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