Deciphering the sequential changes of monocytes/macrophages in the progression of IDD with longitudinal approach using single-cell transcriptome.

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第一作者： Weihang,Li

第一单位： Department of Orthopedic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China.

作者： Weihang,Li ^[1] ; Yingjing,Zhao ^[2] ; Yongchun,Wang ^[3] ; Zhijian,He ^[4] ; Linyuan,Zhang ^[5] ; Bin,Yuan ^[6] ; Chengfei,Li ^[3] ; Zhuojing,Luo ^[1] ; Bo,Gao ^[1] ; Ming,Yan ^[1]

作者单位： Department of Orthopedic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China. ^[1] Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. ^[2] Department of Aerospace Medical Training, School of Aerospace Medicine, Air Force Medical University, Xi'an, China. ^[3] Department of Sports Teaching and Research, Lanzhou University, Lanzhou, China. ^[4] Department of Nursing, Air Force Medical University, Xi'an, China. ^[5] Department of Spine Surgery, Daxing Hospital, Xi'an, Shaanxi, China. ^[6]

关键词 intervertebral disk degeneration longitudinal approach monocytes/macrophage subtypes evolution oxidative?stress single-cell transcriptome landscape trajectory lineage analysis

主题词人类(Humans);单核细胞(Monocytes);碱基序列(Base Sequence);巨噬细胞(Macrophages)

DOI 10.3389/fimmu.2023.1090637

PMID 36817437

发布时间 2023-03-07

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