Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis.

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作者： Yuan,Li ^[1] ; Jialu,Huang ^[1] ; Jie,Wang ^[1] ; Simin,Xia ^[1] ; Hong,Ran ^[1] ; Lenyu,Gao ^[1] ; Chengjian,Feng ^[2] ; Li,Gui ^[3] ; Zhenhua,Zhou ^[1] ; Jichao,Yuan ^[4]

作者单位： Department of Neurology, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Chongqing, 400038, China. ^[1] Department of Traditional Chinese Medicine and Rheumatology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. ^[2] Department of Medical Engineering, 958th Hospital of the People's Liberation Army, Chongqing, 400038, China. ^[3] Department of Neurology, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Chongqing, 400038, China. exploiter001@126.com. ^[4] Department of Neurology, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Chongqing, 400038, China. yuanjichao_tmmu@163.com. ^[5]

关键词 AKT/GSK-3β/β-TrCP/Nrf2 axis Anti-inflammatory phenotype microglia Curcumin Human umbilical cord-derived mesenchymal stem cells Ischemic stroke