首页> Antioxidants (Basel, Switzerland)> Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity.

Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity.

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第一作者： Yihe,Wang

第一单位： Department of Biomedical Sciences, Panum Institute, University of Copenhagen, 2200 Copenhagen, Denmark.

作者： Yihe,Wang ^[1] ; Astrid,Hammer ^[2] ; Gerald,Hoefler ^[3] ; Ernst,Malle ^[4] ; Clare L,Hawkins ^[1] ; Christine Y,Chuang ^[1] ; Michael J,Davies ^[1]

作者单位： Department of Biomedical Sciences, Panum Institute, University of Copenhagen, 2200 Copenhagen, Denmark. ^[1] Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, 8010 Graz, Austria. ^[2] Institute of Pathology, Diagnostic & Research Center for Molecular BioMedicine, Medical University of Graz, 8010 Graz, Austria. ^[3] Division of Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, 8010 Graz, Austria. ^[4]

关键词 ADAMTS MPO-H2O2-Cl? system aggrecan chloramines extracellular matrix hypochlorous acid myeloperoxidase protein oxidation

DOI 10.3390/antiox12020420

PMID 36829979

发布时间 2023-02-28

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Antioxidants (Basel, Switzerland)

2023年12卷2期

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Antioxidants (Basel, Switzerland)

2023年12卷2期

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Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity.

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Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity.

Antioxidants (Basel, Switzerland)

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Antioxidants (Basel, Switzerland)

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