首页> EMBO reports> Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.

Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.

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第一作者： Linbo,Chen

第一单位： State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Responses, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.

作者： Linbo,Chen ^[1] ; Qianping,Zhang ^[1] ; Yuanyuan,Meng ^[1] ; Tian,Zhao ^[1] ; Chenglong,Mu ^[1] ; Changying,Fu ^[1] ; Caijuan,Deng ^[2] ; Jianyu,Feng ^[1] ; Siling,Du ^[1] ; Wei,Liu ^[1] ; Guangfeng,Geng ^[1] ; Kaili,Ma ^[1] ; Hongcheng,Cheng ^[1] ; Qiangqiang,Liu ^[1] ; Qian,Luo ^[1] ; Jiaojiao,Zhang ^[1] ; Zhanqiang,Du ^[1] ; Lin,Cao ^[1] ; Hui,Wang ^[3] ; Yong,Liu ^[3] ; Jianping,Lin ^[2] ; Guo,Chen ^[1] ; Lei,Liu ^[4] ; Sin Man,Lam ^[5] ; Guanghou,Shui ^[6] ; Yushan,Zhu ^[1] ; Quan,Chen ^[1]

作者单位： State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Responses, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China. ^[1] College of Pharmacy, Frontiers Science Center for Cell Responses, Nankai University, Tianjin, China. ^[2] Cancer Institute, Xuzhou Medical University, Xuzhou, China. ^[3] State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. ^[4] State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.;LipidAll Technologies Company Limited, Changzhou, China. ^[5] State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. ^[6]

关键词 FUNDC1 fatty acid metabolism membrane protein dimerization mitochondrial quality control

医学主题词小鼠(Mice);动物(Animals);脂肪酸类(Fatty Acids);二聚作用(Dimerization);线粒体(Mitochondria);线粒体蛋白质类(Mitochondrial Proteins);膜蛋白质类(Membrane Proteins)

DOI 10.15252/embr.202254731

PMID 36847607

发布时间 2024-09-29

基金项目

2019YFA0508603/Ministry of Science and Technology of the People's Republic of China (MOST) 92254304/National Natural Science Foundation of China (NSFC) 32030026/National Natural Science Foundation of China (NSFC) 31271529/National Natural Science Foundation of China (NSFC)

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准确一般字义偏差语意偏离译文作用小提交