GRIN2B gene expression is increased in the anterior cingulate cortex in major depression.

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作者： Samara J,Brown ^[1] ; Amelia M,Brown ^[2] ; Tertia D,Purves-Tyson ^[3] ; Xu-Feng,Huang ^[1] ; Cynthia,Shannon Weickert ^[4] ; Kelly A,Newell ^[5]

作者单位： School of Medical, Indigenous and Health Sciences and Molecular Horizons, University of Wollongong, Wollongong, New South Wales, 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, New South Wales, 2522, Australia. ^[1] Schizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia. ^[2] Schizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia; Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, 2031, Australia. ^[3] Schizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia; Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, 2031, Australia; Department of Neuroscience & Physiology, Upstate Medical University, Syracuse, NY, 13210, USA. ^[4] School of Medical, Indigenous and Health Sciences and Molecular Horizons, University of Wollongong, Wollongong, New South Wales, 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, New South Wales, 2522, Australia. Electronic address: knewell@uow.edu.au. ^[5]

关键词 Anterior cingulate cortex Depression GRIN2B Glutamate NMDA

主题词人类(Humans);抑郁(Depression);抑郁症, 更年期(Depressive Disorder, Major);基因表达(Gene Expression);扣带回(Gyrus Cinguli);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);RNA, 信使(RNA, Messenger)

DOI 10.1016/j.jpsychires.2023.02.017

PMID 36848775

发布时间 2023-04-01

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