Mitochondrial ROS production, oxidative stress and aging within and between species: Evidences and recent advances on this aging effector.

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第一作者： José,Gómez

第一单位： Department of Biology and Geology, Physics and Inorganic Chemistry, ESCET, Rey Juan Carlos University, E28933 Móstoles, Madrid, Spain.

作者： José,Gómez ^[1] ; Natàlia,Mota-Martorell ^[2] ; Mariona,Jové ^[2] ; Reinald,Pamplona ^[3] ; Gustavo,Barja ^[4]

作者单位： Department of Biology and Geology, Physics and Inorganic Chemistry, ESCET, Rey Juan Carlos University, E28933 Móstoles, Madrid, Spain. ^[1] Department of Experimental Medicine, University of Lleida (UdL), Lleida Biomedical Research Institute (IRBLleida), E25198 Lleida, Spain. ^[2] Department of Experimental Medicine, University of Lleida (UdL), Lleida Biomedical Research Institute (IRBLleida), E25198 Lleida, Spain. Electronic address: reinald.pamplona@udl.cat. ^[3] Department of Genetics, Physiology and Microbiology, Faculty of Biological Sciences, Complutense University of Madrid (UCM), E28040 Madrid, Spain. Electronic address: gbarja@bio.ucm.es. ^[4]

关键词 Aging rate Animal longevity Complex I DNA damage DNA fragments Electron transport chain FeS N1a iron-sulfur cluster NDUFV2 subunit