Pyruvate dehydrogenase beta subunit (Pdhb) promotes peripheral axon regeneration by regulating energy supply and gene expression.

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作者： Chunyi,Jiang ^[1] ; Yan,Lu ^[2] ; Ran,Zhu ^[1] ; Ying,Zong ^[1] ; Yuchen,Huang ^[1] ; Dong,Wang ^[1] ; Zhanyun,Da ^[1] ; Bin,Yu ^[1] ; Longxiang,Shen ^[3] ; Qianqian,Cao ^[4]

作者单位： Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Affiliated hospital and Medical School, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China. ^[1] Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Affiliated hospital and Medical School, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China; Clinical Laboratory, Nantong Third Hospital Affiliated to Nantong University, Nantong 226001, China. ^[2] Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China. Electronic address: 7250012700@shsmu.edu.cn. ^[3] Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Affiliated hospital and Medical School, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China. Electronic address: qqcao@ntu.edu.cn. ^[4]

关键词 Axon regeneration Gene expression Glycometabolism Pdhb Peripheral nerve injury

主题词轴突(Axons);神经再生(Nerve Regeneration);丙酮酸脱氢酶(硫辛酰胺)(Pyruvate Dehydrogenase (Lipoamide));基因表达(Gene Expression);乳酸盐类(Lactates);丙酮酸盐类(Pyruvates)

DOI 10.1016/j.expneurol.2023.114368

PMID 36863478

发布时间 2023-04-07

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