Utilization of treatment effect on a surrogate endpoint for planning a study to evaluate treatment effect on a final endpoint.

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作者： Hui,Quan ^[1] ; Zhixing,Xu ^[1] ; Junxiang,Luo ^[2] ; Gautier,Paux ^[1] ; Meehyung,Cho ^[1] ; Xun,Chen ^[1]

作者单位： Biostatistics and Programming, Sanofi, Bridgewater, New Jersey, USA. ^[1] Biostatistics and Programming, Moderna, Cambridge, Massachusetts, USA. ^[2]

关键词 bivariate Bayesian analysis dynamic data borrowing posterior distribution power prior probability of success

主题词人类(Humans);贝叶斯定理(Bayes Theorem);概率(Probability);研究设计(Research Design);样本大小(Sample Size)

DOI 10.1002/pst.2298

PMID 36866697

发布时间 2023-07-18

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Pharmaceutical statistics

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Utilization of treatment effect on a surrogate endpoint for planning a study to evaluate treatment effect on a final endpoint.

Pharmaceutical statistics

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Utilization of treatment effect on a surrogate endpoint for planning a study to evaluate treatment effect on a final endpoint.

Pharmaceutical statistics

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Pharmaceutical statistics

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