Immunogenicity and protective efficacy of a multi-epitope recombinant toxin antigen of Pasteurella multocida against virulent challenge in mice.

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第一作者： Wei,Liang

第一单位： Research Center of Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

作者： Wei,Liang ^[1] ; Hang,Xiao ^[1] ; Jia-Yong,Chen ^[1] ; Yung-Fu,Chang ^[2] ; San-Jie,Cao ^[3] ; Yi-Ping,Wen ^[3] ; Rui,Wu ^[3] ; Sen-Yan,Du ^[3] ; Qi-Gui,Yan ^[3] ; Xiao-Bo,Huang ^[3] ; Qin,Zhao ^[4]

作者单位： Research Center of Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. ^[1] Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA. ^[2] Research Center of Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China; Sichuan Science-Observation Experimental Station of Veterinary Drugs and Veterinary Diagnostic Technique, Ministry of Agriculture and Rural Affairs, Chengdu 611130, China; National Demonstration Center for Experimental Animal Education, Sichuan Agricultural University, Chengdu 611130, China. ^[3] Research Center of Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China; Sichuan Science-Observation Experimental Station of Veterinary Drugs and Veterinary Diagnostic Technique, Ministry of Agriculture and Rural Affairs, Chengdu 611130, China; National Demonstration Center for Experimental Animal Education, Sichuan Agricultural University, Chengdu 611130, China. Electronic address: zhao.qin@sicau.edu.cn. ^[4]

关键词 Epitope Immunogenicity Mice Multi-epitope recombinant antigen of PMT (rPMT)Pasteurella multocida toxin (PMT)