Chemical and <i>in vitro</i> toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette.
第一作者:
Tsuneo,Hashizume
第一单位:
Scientific Product Assessment Center, R&D Group, Japan Tobacco Inc., Yokohama, 6-2 Umegaoka, Aoba-ku, Kanagawa 227-8512, Japan.
作者:
关键词
ACM, aerosol collected massARE, anti-oxidant responsive elementAqE, aqueous extractBDL, below detection limitCMF-PBS, calcium- and magnesium-free phosphate buffered salineCS, cigarette smokeCytotoxicityDT3.0a, Direct Heating Tobacco System Platform 3 generation 3 version aGFP, green fluorescent proteinGVP, gas-vapor phaseGenotoxicityHPHCsHPHCs, harmful and potentially harmful constituentsHTP, heated tobacco productHeated tobacco productIC50, half maximal inhibitory concentrationISO, International Organization for StandardizationIn vitroLOD, limit of detectionLOQ, limit of quantificationMLA, mouse lymphoma assayMN, micronucleusMRTP, modified risk tobacco productNQ, not quantifiedNRU, neutral red uptakeOxidative stressROS, reactive oxygen speciesTHP, tobacco heating productTHS, tobacco heating systemTPM, total particulate mattermES, mouse embryonic stem
DOI
10.1016/j.toxrep.2023.02.005
PMID
36876026
发布时间
2023-03-07
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Toxicology reports
2023年10卷
281-292页
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