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首页> Diabetes research and clinical practice> Reduction of mRNA m<sup>6</sup>A associates with glucose metabolism via YTHDC1 in human and mice.

Reduction of mRNA m<sup>6</sup>A associates with glucose metabolism via YTHDC1 in human and mice.

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作者： Kun,Yang ^[1] ; Juan,Sun ^[2] ; Zijie,Zhang ^[3] ; Mengyao,Xiao ^[1] ; Decheng,Ren ^[4] ; Song-Mei,Liu ^[5]

作者单位： Department of Clinical Laboratory, Center for Gene Diagnosis, and Program of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province 430071, China. ^[1] Department of Neurobiology, The University of Chicago, 5841, S. Maryland Avenue, MC 1027, Chicago, IL 60637, USA. ^[2] Department of Chemistry, The University of Chicago, 5841, S. Maryland Avenue, MC 1027, Chicago, IL 60637, USA. ^[3] Department of Medicine, The University of Chicago, 5841 S. Maryland Avenue, MC 1027, Chicago, IL 60637, USA. Electronic address: ren_decheng@lilly.com. ^[4] Department of Clinical Laboratory, Center for Gene Diagnosis, and Program of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province 430071, China. Electronic address: smliu@whu.edu.cn. ^[5]

关键词 Glucose metabolism M(6)A Type 2 diabetes YTHDC1 β-cell

主题词人类(Humans);小鼠(Mice);动物(Animals);RNA, 信使(RNA, Messenger);糖尿病, 2型(Diabetes Mellitus, Type 2);串联质谱法(Tandem Mass Spectrometry);葡萄糖(Glucose);胰岛素分泌细胞(Insulin-Secreting Cells);神经组织蛋白质类(Nerve Tissue Proteins)

DOI 10.1016/j.diabres.2023.110607

PMID 36878322

发布时间 2023-04-11

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