Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial.

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第一作者： Robert S,Rosenson

第一单位： Metabolism and Lipids Unit, Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY, USA. robert.rosenson@mssm.edu.

作者： Robert S,Rosenson ^[1] ; Daniel,Gaudet ^[2] ; Christie M,Ballantyne ^[3] ; Seth J,Baum ^[4] ; Jean,Bergeron ^[5] ; Erin E,Kershaw ^[6] ; Patrick M,Moriarty ^[7] ; Paolo,Rubba ^[8] ; David C,Whitcomb ^[9] ; Poulabi,Banerjee ^[10] ; Andrew,Gewitz ^[10] ; Claudia,Gonzaga-Jauregui ^[10] ; Jennifer,McGinniss ^[10] ; Manish P,Ponda ^[10] ; Robert,Pordy ^[10] ; Jian,Zhao ^[10] ; Daniel J,Rader ^[11]

作者单位： Metabolism and Lipids Unit, Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY, USA. robert.rosenson@mssm.edu. ^[1] Clinical Lipidology and Rare Lipid Disorders Unit, Department of Medicine, Université de Montréal Community Gene Medicine Center, and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada. ^[2] Department of Medicine, Baylor College of Medicine, Houston, TX, USA. ^[3] Excel Medical Clinical Trials and Department of Integrated Medical Sciences, Charles E Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA. ^[4] Departments of Laboratory Medicine and of Medicine, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, Québec, Canada. ^[5] Division of Endocrinology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. ^[6] Division of Clinical Pharmacology, University of Kansas Medical Center, Kansas City, KS, USA. ^[7] Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy. ^[8] Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, PA, USA. ^[9] Regeneron Pharmaceuticals, Tarrytown, NY, USA. ^[10] Department of Genetics and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ^[11]