Patient-derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma.

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第一作者： Lisa Kristina,Isbell

第一单位： Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

作者： Lisa Kristina,Isbell ^[1] ; Cordula,Tschuch ^[2] ; Soroush,Doostkam ^[3] ; Silvia,Waldeck ^[1] ; Geoffroy,Andrieux ^[4] ; Khalid,Shoumariyeh ^[5] ; Dorothee,Lenhard ^[1] ; Hans Eckart,Schaefer ^[5] ; Peter Christoph,Reinacher ^[2] ; Ingrid,Bartsch ^[6] ; Milena,Pantic ^[7] ; Janaki Manoja,Vinnakota ^[8] ; Vinodh,Kakkassery ^[1] ; Elisabeth,Schorb ^[1] ; Florian,Scherer ^[1] ; Anna Verena,Frey ^[9] ; Melanie,Boerries ^[1] ; Gerald,Illerhaus ^[1] ; Justus,Duyster ^[5] ; Julia,Schueler ^[6] ; Nikolas,von Bubnoff ^[4]

作者单位： Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany. ^[1] Charles River Discovery Research Services GmbH, Freiburg, Germany. ^[2] Institute of Neuropathology, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany. ^[3] Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany. ^[4] German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[5] Department of Pathology, University of Freiburg, Freiburg, Germany. ^[6] Department of Stereotactic and Functional Neurosurgery, Medical Faculty, University of Freiburg, Freiburg, Germany. ^[7] Fraunhofer Institute for Laser Technology (ILT), Aachen, Germany. ^[8] Department of Ophthalmology, University of Luebeck, Luebeck, Germany. ^[9] Clinic of Hematology, Oncology and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany. ^[10] Department of Hematology and Oncology, University Hospital Schleswig-Holstein, Luebeck, Germany. ^[11]

关键词 CNS tropism patient-derived xenograft primary and secondary central nervous system lymphoma primary vitreoretinal lymphoma