Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling.

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作者： Mariah,Farrell ^[1] ; Heather,Fairfield ^[2] ; Michelle,Karam ^[3] ; Anastasia,D'Amico ^[1] ; Connor S,Murphy ^[2] ; Carolyne,Falank ^[3] ; Romanos Sklavenitis,Pistofidi ^[1] ; Amanda,Cao ^[1] ; Catherine R,Marinac ^[1] ; Julie A,Dragon ^[2] ; Lauren,McGuinness ^[1] ; Carlos G,Gartner ^[4] ; Reagan Di,Iorio ^[5] ; Edward,Jachimowicz ^[4] ; Victoria,DeMambro ^[5] ; Calvin,Vary ^[4] ; Michaela R,Reagan ^[5]

作者单位： Center for Molecular Medicine, Maine Health Institute for Research, Scarborough, United States. ^[1] Graduate School of Biomedical Science and Engineering, University of Maine, Orono, United States. ^[2] Tufts University School of Medicine, Boston, United States. ^[3] Dana-Farber Cancer Institute, Boston, United States. ^[4] Harvard Medical School, Boston, United States. ^[5] University of Vermont, Burlington, United States. ^[6] University of New England, Biddeford, United States. ^[7]

关键词 FABP FABP5 RNA-Seq cancer biology fatty acid binding protein myeloma proteomics

主题词动物(Animals);小鼠(Mice);多发性骨髓瘤(Multiple Myeloma);蛋白质组学(Proteomics);细胞周期(Cell Cycle);脂肪酸结合蛋白质类(Fatty Acid-Binding Proteins)

DOI 10.7554/eLife.81184

PMID 36880649

发布时间 2024-05-10

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准确一般字义偏差语意偏离译文作用小提交