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Atrophy signaling pathways in respiratory and limb muscles of guinea pigs exposed to chronic cigarette smoke: role of soluble guanylate cyclase stimulation.

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第一作者： Víctor Ivo,Peinado

第一单位： Department of Pulmonary Medicine, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.;Department of Experimental Pathology, Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC-IDIBAPS, Barcelona, Spain.;Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.

作者： Víctor Ivo,Peinado ^[1] ; Maria,Guitart ^[2] ; Isabel,Blanco ^[3] ; Olga,Tura-Ceide ^[4] ; Tanja,Paul ^[5] ; Joan Albert,Barberà ^[3] ; Esther,Barreiro ^[2]

作者单位： Department of Pulmonary Medicine, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.;Department of Experimental Pathology, Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC-IDIBAPS, Barcelona, Spain.;Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain. ^[1] Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.;Respiratory Medicine Department, Muscle & Lung Cancer Research group, IMIM-Hospital del Mar, Parc de Salut Mar, MELIS, UPF, PRBB, Barcelona, Spain. ^[2] Department of Pulmonary Medicine, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.;Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain. ^[3] Department of Pulmonary Medicine, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.;Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.;Pneumology Department, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. ^[4] Faculty of Medicine, Institute of Pathology, Ludwig-Maximilians University Munich, Munich, Germany. ^[5]

关键词 COPD cGMP muscle atrophy pharmacology

主题词豚鼠(Guinea Pigs);动物(Animals);鸟苷酸环化酶(Guanylate Cyclase);肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive);肌, 骨骼(Muscle, Skeletal);信号传导(Signal Transduction);萎缩(Atrophy)

DOI 10.1152/ajplung.00258.2022

PMID 36881560

发布时间 2023-05-03

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