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Chemotherapy induces immune checkpoint VISTA expression in tumor cells via HIF-2alpha.

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第一作者： Na,Li

第一单位： Department of Dermatology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China; School of Medicine, Ningbo University, Ningbo, China.

作者： Na,Li ^[1] ; Shanru,Yang ^[2] ; Yan,Ren ^[3] ; Risheng,Tai ^[4] ; Hua,Liu ^[3] ; Yixuan,Wang ^[3] ; Jianing,Li ^[3] ; Fuyan,Wang ^[3] ; Jingjun,Xing ^[3] ; Yanru,Zhang ^[3] ; Xiaoxia,Zhu ^[5] ; Suling,Xu ^[5] ; Xin,Hou ^[6] ; Geng,Wang ^[7]

作者单位： Department of Dermatology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China; School of Medicine, Ningbo University, Ningbo, China. ^[1] Department of Histology and Embryology, Harbin Medical University, Harbin, China; Department of Pathology, the First Hospital of Lanzhou University, Lanzhou, China. ^[2] School of Medicine, Ningbo University, Ningbo, China. ^[3] Department of Histology and Embryology, Harbin Medical University, Harbin, China; The First Psychiatric Hospital of Harbin, Heilongjiang, China. ^[4] Department of Dermatology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China. ^[5] School of Medicine, Ningbo University, Ningbo, China. Electronic address: houxin@nbu.edu.cn. ^[6] School of Medicine, Ningbo University, Ningbo, China. Electronic address: wanggeng@nbu.edu.cn. ^[7]

关键词 Chemotherapy HIF-2α Immune evasion Melanoma VISTA

医学主题词人类(Humans);肿瘤复发, 局部(Neoplasm Recurrence, Local);适应性免疫(Adaptive Immunity);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors)

DOI 10.1016/j.bcp.2023.115492

PMID 36898416

发布时间 2023-03-29

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