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Characterization of human anti-EpCAM antibodies for developing an antibody-drug conjugate.

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作者单位: Chromosome Engineering Research Center, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. [1] Department of Chromosome Biomedical Engineering, School of Life Science, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. [2] Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, 150081, Heilongjiang, China. [3] Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. [4] Research Institute for Diseases of Old Age, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. [5] Department of Neurology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. [6] Department of Chemistry and Bioscience, Graduate School of Science and Engineering, University of Kagoshima, 1-21-40 Korimoto, Kagoshima, 890-0065, Japan. [7] Trans Chromosomics Inc., 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. [8] Division of Genome and Cellular Functions, Integrated Medical Sciences, Graduate School of Medical Science, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. [9] Order-Made Medical Research Inc., 5-4-19 Kashiwanoha, Kashiwa, Chiba, 277-0882, Japan. [10] Chromosome Engineering Research Center, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. kazuki@tottori-u.ac.jp. [11] Department of Chromosome Biomedical Engineering, School of Life Science, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. kazuki@tottori-u.ac.jp. [12] Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. kazuki@tottori-u.ac.jp. [13] Division of Genome and Cellular Functions, Integrated Medical Sciences, Graduate School of Medical Science, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. kazuki@tottori-u.ac.jp. [14]
DOI 10.1038/s41598-023-31263-x
PMID 36918661
发布时间 2023-04-18
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