Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies.

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作者： Charlotte,Roth ^[1] ; Helena,Kilpinen ^[2] ; Manju A,Kurian ^[3] ; Serena,Barral ^[1]

作者单位： Molecular Neurosciences, Developmental Neurosciences Programme, Zayed Centre for Research into Rare Disease in Children, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom. ^[1] Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland. ^[2] Molecular Neurosciences, Developmental Neurosciences Programme, Zayed Centre for Research into Rare Disease in Children, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.;Department of Neurology, Great Ormond Street Hospital for Children, London, United Kingdom. ^[3]

关键词 brain organoids epigenetics (chromatin remodeling)histone lysine methyltransferases (HKMTs)neurodevelopmental disorders (NDDs)small-activating RNA (saRNA)

DOI 10.3389/fcell.2023.1090046

PMID 36923252

发布时间 2024-09-14

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Frontiers in cell and developmental biology

2023年11卷

1090046页

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Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies.

Frontiers in cell and developmental biology

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Frontiers in cell and developmental biology

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Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies.

Frontiers in cell and developmental biology

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Frontiers in cell and developmental biology

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