A genome-wide CRISPR activation screen identifies <i>SCREEM</i> a novel <i>SNAI1</i> super-enhancer demarcated by eRNAs.

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作者： Dinesh Babu,Uthaya Kumar ^[1] ; Marina,Yurieva ^[2] ; Jessica,Grassmann ^[1] ; Lina,Kozhaya ^[1] ; Caleb Dante,McBride ^[1] ; Derya,Unutmaz ^[3] ; Adam,Williams ^[1]

作者单位： The Jackson Laboratory for Genomic Medicine, Farmington, CT, United States. ^[1] The Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT, United States. ^[2] Department of Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. ^[3]

关键词 CD44 CRISPR-screen EMT SNAI1 eRNA lncRNA monocytes

DOI 10.3389/fmolb.2023.1110445

PMID 36923642

发布时间 2024-05-18

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Frontiers in molecular biosciences

2023年10卷

1110445页

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A genome-wide CRISPR activation screen identifies <i>SCREEM</i> a novel <i>SNAI1</i> super-enhancer demarcated by eRNAs.

Frontiers in molecular biosciences

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Frontiers in molecular biosciences

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A genome-wide CRISPR activation screen identifies <i>SCREEM</i> a novel <i>SNAI1</i> super-enhancer demarcated by eRNAs.

Frontiers in molecular biosciences

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Frontiers in molecular biosciences

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