A novel rare variant of CNPY3 from familial NMOSD impairs the TLR-mediated immune response.

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作者： Yongxin,Mo ^[1] ; Shisi,Wang ^[1] ; Yanyu,Chang ^[2] ; Xiaobo,Sun ^[1] ; Zheng,Liu ^[2] ; Ping,Sun ^[3] ; Yan,Xu ^[4] ; Xiaofen,Zhong ^[5] ; Lisheng,Peng ^[6]

作者单位： Department of Neurology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. ^[1] Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. ^[2] Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, China. ^[3] Biotherapy Centre, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. ^[4] Biotherapy Centre, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. Electronic address: zhongxf29@mail.sysu.edu.cn. ^[5] Department of Neurology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. Electronic address: penglsh5@mail.sysu.edu.cn. ^[6]

关键词 Autoimmune CNPY3 NMOSD TLR

主题词动物(Animals);小鼠(Mice);免疫(Immunity);白细胞介素6(Interleukin-6);脂多糖类(Lipopolysaccharides);小鼠, 转基因(Mice, Transgenic);视神经脊髓炎(Neuromyelitis Optica);Toll样受体4(Toll-Like Receptor 4);Toll样受体(Toll-Like Receptors)

DOI 10.1016/j.jneuroim.2023.578065

PMID 36931208

发布时间 2023-08-10

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Journal of neuroimmunology

2023年377卷

578065页

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A novel rare variant of CNPY3 from familial NMOSD impairs the TLR-mediated immune response.

Journal of neuroimmunology

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Journal of neuroimmunology

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A novel rare variant of CNPY3 from familial NMOSD impairs the TLR-mediated immune response.

Journal of neuroimmunology

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Journal of neuroimmunology

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