Plasma levels of bone morphogenic protein-4 are downregulated in elderly hypertensive patients with heart failure with preserved ejection fraction.

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第一作者： Ying,Guo

第一单位： Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

作者： Ying,Guo ^[1] ; Ning,Wang ^[1] ; Ying,Dong ^[2] ; Xueting,Li ^[2] ; Qian,Liu ^[3] ; Qi,Liu ^[3] ; Guohong,Wang ^[3] ; Mingzhao,Qin ^[3] ; Zhenzhou,Zhang ^[2] ; Jiawei,Song ^[4] ; Ying,Liu ^[5] ; Hongjie,Chi ^[5] ; Jiuchang,Zhong ^[6]

作者单位： Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China. ^[1] Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. ^[2] Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China. ^[3] Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. ^[4] Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. ^[5] Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. Electronic address: jczhong@sina.com. ^[6]

关键词 Bone morphogenic protein-4 Heart failure with mildly reduced ejection fraction Heart failure with preserved ejection fraction Hypertension

主题词人类(Humans);老年人(Aged);心力衰竭(Heart Failure);每搏输出量(Stroke Volume);利钠肽, 脑(Natriuretic Peptide, Brain);高血压(Hypertension);预后(Prognosis)

DOI 10.1016/j.clinbiochem.2023.03.008

PMID 36935066

发布时间 2023-05-22

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