Preparation, characterization and safety evaluation of Ligusticum chuanxiong essential oils liposomes for treatment of cerebral ischemia-reperfusion injury.

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作者： Yu,Long ^[1] ; Shuang,Yu ^[2] ; Dan,Li ^[3] ; Ai,Shi ^[4] ; Yin,Ma ^[5] ; Jie,Deng ^[6] ; Xiao-Qiu,Li ^[7] ; Jing,Wen ^[8] ; Yuan-Yuan,Wu ^[9] ; Yue,Hu ^[10] ; Xiao-Fang,He ^[11] ; Nan,Li ^[12] ; Li,Han ^[13] ; Juan,Du ^[14]

作者单位： State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1548650993@qq.com. ^[1] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1509066024@qq.com. ^[2] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: ldaptx4869@163.com. ^[3] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1923348477@qq.com. ^[4] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 2245893402@qq.com. ^[5] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1399380644@qq.com. ^[6] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1972917746@qq.com. ^[7] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 981804860@qq.com. ^[8] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1360082446@qq.com. ^[9] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 827367775@qq.com. ^[10] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 1215186218@qq.com. ^[11] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 55743198@qq.com. ^[12] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 2900480797@qq.com. ^[13] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Electronic address: 80407022@qq.com. ^[14]

关键词 Cerebral ischemia-reperfusion injury Characterization Essential oil Ligusticum chuanxiong Hort Liposome Preparation Safety evaluation

主题词小鼠(Mice);动物(Animals);油类, 挥发(Oils, Volatile);脂质体(Liposomes);藁木属(Ligusticum);中草药(Drugs, Chinese Herbal);再灌注损伤(Reperfusion Injury)

DOI 10.1016/j.fct.2023.113723

PMID 36935074

发布时间 2023-04-11

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