Recombinant Fusion Protein Vaccine Containing Clostridioides difficile FliC and FliD Protects Mice against C. difficile Infection.

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作者： Shaohui,Wang ^[1] ; Xianghong,Ju ^[2] ; Joshua,Heuler ^[1] ; Keshan,Zhang ^[2] ; Zhibian,Duan ^[1] ; Hiran Malinda Lamabadu,Warnakulasuriya Patabendige ^[1] ; Song,Zhao ^[2] ; Xingmin,Sun ^[1]

作者单位： Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA. ^[1] Department of Infectious Diseases and Global Health, Tufts University Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA. ^[2]

关键词 Clostridioides difficile infection (CDI)FliCD chimeric protein vaccine hyperimmune serum

主题词动物(Animals);小鼠(Mice);重组融合蛋白质类(Recombinant Fusion Proteins);梭菌感染(Clostridium Infections);细菌蛋白质类(Bacterial Proteins);细菌菌苗(Bacterial Vaccines)

DOI 10.1128/iai.00169-22

PMID 36939332

发布时间 2023-09-21

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