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Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice.

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第一作者： Hui,Yang

第一单位： Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.

作者： Hui,Yang ^[1] ; Xinzhi,Wang ^[2] ; Pin,Wang ^[3] ; Li,He ^[4] ; Suzyann F,Schick ^[5] ; Peyton,Jacob ^[6] ; Neal,Benowitz ^[6] ; Lara A,Gundel ^[7] ; Chi,Zhu ^[8] ; Yankai,Xia ^[9] ; Jamie L,Inman ^[10] ; Hang,Chang ^[10] ; Antoine M,Snijders ^[11] ; Jian-Hua,Mao ^[12] ; Bo,Hang ^[13]

作者单位： Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China. ^[1] College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China. ^[2] Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China. ^[3] Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China. ^[4] Department of Medicine, Division of Occupational and Environmental Medicine, University of California, San Francisco, CA 94143, USA. ^[5] Department of Medicine, Division of Cardiology, Clinical Pharmacology Program, University of California, San Francisco, CA 94143, USA. ^[6] Indoor Environment Group, Energy Technologies Area, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. ^[7] Hanszen College, Rice University, Houston, TX 77005, USA. ^[8] State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China. ^[9] Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. ^[10] Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: amsnijders@lbl.gov. ^[11] Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: jhmao@lbl.gov. ^[12] Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: Bo_Hang@lbl.gov. ^[13]

关键词 Collaborative Cross (CC) mice Genetic susceptibility Pan-tumor incidence Thirdhand smoke (THS)Tumor burden Tumor-free survival Tumorigenesis

主题词人类(Humans);动物(Animals);小鼠(Mice);烟草烟污染(Tobacco Smoke Pollution);危险因素(Risk Factors);肿瘤(Neoplasms);细胞转化, 肿瘤(Cell Transformation, Neoplastic)

DOI 10.1016/j.envint.2023.107876

PMID 36940581

发布时间 2024-09-30

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