RAS degraders: The new frontier for RAS-driven cancers.

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作者： Taylor E,Escher ^[1] ; Karla J F,Satchell ^[2]

作者单位： Department of Microbiology-Immunology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Research Center, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA. ^[1] Department of Microbiology-Immunology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Research Center, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: k-satchell@northwestern.edu. ^[2]

关键词 PROTACs RAS RRSP degraders

主题词人类(Humans);肿瘤(Neoplasms);蛋白质类(Proteins);内肽酶类(Endopeptidases);ras蛋白质类(ras Proteins);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1016/j.ymthe.2023.03.017

PMID 36945775

发布时间 2024-07-06

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