Flavonoids derived from licorice suppress LPS-induced acute lung injury in mice by inhibiting the cGAS-STING signaling pathway.

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作者： Jincai,Wen ^[1] ; Shuanglin,Qin ^[2] ; Yurong,Li ^[3] ; Ping,Zhang ^[4] ; Xiaoyan,Zhan ^[5] ; Mingxia,Fang ^[5] ; Ce,Shi ^[5] ; Wenqing,Mu ^[5] ; Wen,Kan ^[5] ; Jia,Zhao ^[5] ; Siwen,Hui ^[5] ; Manting,Hou ^[1] ; Hui,Li ^[5] ; Xiaohe,Xiao ^[6] ; Guang,Xu ^[7] ; Zhaofang,Bai ^[8]

作者单位： School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China; Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. ^[1] Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, PR China. ^[2] Department of Military Patient Management, The Fifth Medical Center of PLA General Hospital, Beijing, 100039, China. ^[3] Department of Pharmacy, Medical Supplies Center of PLA General Hospital, Beijing, 100039, China. ^[4] Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. ^[5] School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China; Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. Electronic address: pharmacy_302@126.com. ^[6] Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China. Electronic address: guang_xu@ccmu.edu.cn. ^[7] Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. Electronic address: baizf2008@hotmail.com. ^[8]

关键词 Bronchoalveolar lavage fluid LPS-Induced acute lung injury Licorice flavonoids cGAS-STING