Pulmonary artery smooth muscle cell phenotypic switching: A key event in the early stage of pulmonary artery hypertension.

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作者： Binghao,Ma ^[1] ; Yuanyuan,Cao ^[1] ; Jia,Qin ^[1] ; Zhuo,Chen ^[1] ; Gaoyun,Hu ^[1] ; Qianbin,Li ^[2]

作者单位： Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China; Hunan Key Laboratory of Small Molecules for Diagnosis and Treatment of Chronic Disease, Changsha 410013, Hunan, China; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China. ^[1] Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China; Hunan Key Laboratory of Small Molecules for Diagnosis and Treatment of Chronic Disease, Changsha 410013, Hunan, China; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China. Electronic address: qbli@csu.edu.cn. ^[2]

关键词 early stage phenotypic switching pulmonary arterial hypertension pulmonary smooth muscle cells signaling pathways small molecular regulators

主题词人类(Humans);肺动脉(Pulmonary Artery);高血压, 肺性(Hypertension, Pulmonary);信号传导(Signal Transduction);肌细胞, 平滑肌(Myocytes, Smooth Muscle);细胞增殖(Cell Proliferation)

DOI 10.1016/j.drudis.2023.103559

PMID 36958640

发布时间 2023-05-13

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