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The Glioma-IRE project - Molecular profiling in patients with glioma: steps toward an individualized diagnostic and therapeutic approach.

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第一作者： Veronica,Villani

第一单位： Neuro-Oncology Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. veronica.villani@ifo.it.

作者： Veronica,Villani ^[1] ; Beatrice,Casini ^[2] ; Antonio,Tanzilli ^[3] ; Mario,Lecce ^[4] ; Fabrizio,Rasile ^[4] ; Stefano,Telera ^[4] ; Andrea,Pace ^[3] ; Francesca,Piludu ^[5] ; Irene,Terrenato ^[6] ; Francesca,Rollo ^[2] ; Francesca,De Nicola ^[7] ; Maurizio,Fanciulli ^[7] ; Matteo,Pallocca ^[6] ; Gennaro,Ciliberto ^[8] ; Mariantonia,Carosi ^[2]

作者单位： Neuro-Oncology Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. veronica.villani@ifo.it. ^[1] Pathology Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. ^[2] Neuro-Oncology Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. ^[3] Division of Neurosurgery, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. ^[4] Radiology and Diagnostic Imaging Department, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. ^[5] UOSD Clinical Trial Center Biostatistics and Bioinformatics, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. ^[6] Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. ^[7] Scientific Direction, IRCCS National Cancer Institute Regina Elena, Via Elio Chianesi 53, 00144, Rome, Italy. ^[8]

关键词 Glioblastoma Glioma Molecular profiling Next-generation sequencing Precision medicine

医学主题词人类(Humans);神经胶质瘤(Glioma);胶质母细胞瘤(Glioblastoma);突变(Mutation);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);DNA拷贝数变异(DNA Copy Number Variations);脑肿瘤(Brain Neoplasms)

DOI 10.1186/s12967-023-04057-y

PMID 36959606

发布时间 2023-04-03

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