mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.

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作者： Marion,Moreews ^[1] ; Anne-Laure,Mathieu ^[1] ; Kevin,Pouxvielh ^[1] ; Quentin,Reuschlé ^[2] ; Annabelle,Drouillard ^[1] ; Pénélope,Dessay ^[1] ; Marie,Meignien ^[1] ; Jiang,Zhang ^[3] ; Lucie,Fallone ^[1] ; Noëmi,Rousseaux ^[1] ; Michelle,Ainouze ^[1] ; Amaury,Rey ^[1] ; Ommar,Omarjee ^[1] ; Elodie,Decembre ^[1] ; Vanina,Lenief ^[1] ; Sophia,Djebali ^[1] ; Olivier,Thaunat ^[1] ; Marlène,Dreux ^[1] ; Laurent,Genestier ^[4] ; Thierry,Defrance ^[5] ; Pauline,Soulas-Sprauel ^[1] ; Antoine,Marçais ^[1] ; Thierry,Walzer ^[1] ; Alexandre,Belot ^[2]

作者单位： CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France. ^[1] INSERM UMR-S1109, Department of Clinical Immunology and Internal Medicine, National Reference Center for Systemic Autoimmune Diseases, Tertiary Center for Primary Immunodeficiency, Faculty of Pharmacy, Université de Strasbourg, Strasbourg, France. ^[2] Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, Lyon, France. ^[3] Department of Transplantation, Nephrology and Clinical Immunology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France. ^[4] Lyon-Est Medical Faculty, Claude Bernard University (Lyon 1), Lyon, France. ^[5]