circNEIL3 inhibits tumor metastasis through recruiting the E3 ubiquitin ligase Nedd4L to degrade YBX1.

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作者： Shuang,Chen ^[1] ; Ke,Li ^[1] ; Jiawei,Guo ^[1] ; Hai-Ning,Chen ^[2] ; Yue,Ming ^[1] ; Yang,Jin ^[1] ; Fuyan,Xu ^[1] ; Tingting,Zhang ^[1] ; Yang,Yang ^[1] ; Zixia,Ye ^[1] ; Wenrong,Liu ^[1] ; Hulin,Ma ^[1] ; Jian,Cheng ^[1] ; Jian-Kang,Zhou ^[1] ; Zhang,Li ^[1] ; Shu,Shen ^[1] ; Lunzhi,Dai ^[3] ; Zong-Guang,Zhou ^[2] ; Heng,Xu ^[3] ; Yong,Peng ^[1]

作者单位： Laboratory of Molecular Oncology, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China. ^[1] Colorectal Cancer Center, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. ^[2] State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China. ^[3]

关键词 Nedd4L YBX1 circRNA metastasis

主题词人类(Humans);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);结直肠肿瘤(Colorectal Neoplasms);Y盒结合蛋白质1(Y-Box-Binding Protein 1)

DOI 10.1073/pnas.2215132120

PMID 36961927

发布时间 2023-09-25

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